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Friday, November 8, 2013

ScienceDaily: Top Health News

ScienceDaily: Top Health News


Novel genetic patterns may make us rethink biology and individuality

Posted: 07 Nov 2013 05:42 PM PST

Scientists have made two novel discoveries: 1) a person can have several DNA mutations in parts of their body, with their original DNA in the rest -- resulting in several different genotypes in one individual -- and 2) some of the same genetic mutations occur in unrelated people. We think of each person's DNA as unique, but if a person can have more than one genotype, this may have broad implications.

Bacterial toxin sets the course for infection

Posted: 07 Nov 2013 05:42 PM PST

Every year gastro-intestinal diseases have lethal consequences for more than five million individuals. Scientists have now discovered what makes a specific strain of Yersinia pseudotuberculosis so dangerous: the bacteria produce a molecule called CNFy that facilitates the infection process for them. It changes the host cells in a manner that enables the injection apparatus of Yersinia, which injects toxins into the cells, to work more efficiently. This strengthens the gastrointestinal infection and leads to inflammation of the tissue.

How body clock affects inflammation: Discovery could accelerate body's response to infection, autoimmune disorders

Posted: 07 Nov 2013 02:06 PM PST

Researchers report that disrupting the light-dark cycle of mice increased their susceptibility to inflammatory disease, indicating that the production of a key immune cell is controlled by the body's circadian clock.

Tobacco myths persist 50 years after US Surgeon General warned Americans of smoking dangers

Posted: 07 Nov 2013 11:24 AM PST

Tobacco misconceptions prevail in the United States despite the dramatic drop in smoking rates since the release of the first Surgeon General's Report on smoking and health in January 1964. Cancer experts dispel common myths and share new educational resources to address this persistent challenge.

Small RNA molecule in blood could help diagnose pancreatic cancer

Posted: 07 Nov 2013 11:24 AM PST

A cancer researcher has demonstrated that a particular molecule is present in the blood of most pancreatic cancer patients, suggesting it could someday be a diagnostic marker for the disease.

New method predicts time from Alzheimer’s onset to nursing home, death

Posted: 07 Nov 2013 11:24 AM PST

A research team has clinically validated a new method for predicting time to nursing home residence or death for patients with Alzheimer's. The method uses data from a single patient visit, and is based on a complex model of Alzheimer's progression developed by consecutively following two sets of Alzheimer's patients for 10 years each.

Hope builds for drug that might shut down variety of cancers

Posted: 07 Nov 2013 10:28 AM PST

The most frequently mutated gene across all types of cancers is a gene called p53. Unfortunately it has been difficult to directly target this gene with drugs. Now a multi-institutional research team has identified a family of enzymes they say is crucial for the growth of cancers that have genetic aberrations in p53.

For obese teen girls, aerobic exercise may trump resistance training in health benefits

Posted: 07 Nov 2013 09:32 AM PST

New findings suggest that for teen girls, aerobic exercise might be superior to resistance exercise for cutting health risks associated with obesity.

Obesity may limit overall function two years after shoulder replacement surgery

Posted: 07 Nov 2013 09:32 AM PST

Patients with obesity undergo a disproportionately higher number of elective orthopaedic surgeries in the US. Obesity has been linked to higher costs, complications, infections and revisions in total knee and total hip replacement surgeries.

Researchers regrow hair, cartilage, bone, soft tissues: Enhancing cell metabolism was an unexpected key to tissue repair

Posted: 07 Nov 2013 09:31 AM PST

Young animals are known to repair their tissues effortlessly, but can this capacity be recaptured in adults? A new study suggests that it can. By reactivating a dormant gene called Lin28a, which is active in embryonic stem cells, researchers were able to regrow hair and repair cartilage, bone, skin and other soft tissues in a mouse model.

Muscle built in diseased mice: Human muscle cells created in a dish

Posted: 07 Nov 2013 09:31 AM PST

Skeletal muscle has proved to be very difficult to grow in patients with muscular dystrophy and other disorders that degrade and weaken muscle. Researchers now report boosting muscle mass and reversing disease in a mouse model of Duchenne muscular dystrophy, using a "cocktail" of three compounds identified through a new rapid culture system. Adding the same compounds to stem cells derived from patients' skin cells, they then successfully grew human muscle cells in a dish.

Social symptoms in autistic children may be caused by hyper-connected neurons

Posted: 07 Nov 2013 09:30 AM PST

The brains of children with autism show more connections than the brains of typically developing children do. What's more, the brains of individuals with the most severe social symptoms are also the most hyper-connected. The findings reported in two independent studies are challenge the prevailing notion in the field that autistic brains are lacking in neural connections.

Researchers discover new driver of breast cancer

Posted: 07 Nov 2013 09:27 AM PST

A team of researchers has found that as cholesterol is metabolized, a potent stimulant of breast cancer is created – one that fuels estrogen-receptor positive breast cancers, and that may also defeat a common treatment strategy for those cancers.

Scientists identify clue to regrowing nerve cells

Posted: 07 Nov 2013 09:27 AM PST

Researchers have identified a chain reaction that triggers the regrowth of some damaged nerve cell branches, a discovery that one day may help improve treatments for nerve injuries that can cause loss of sensation or paralysis.

Clotting protein hardens aging hearts

Posted: 07 Nov 2013 07:38 AM PST

A researcher has found through studies of pigs' heart valves that age plays a critical role in the valves' progressive hardening, and the problem may be due to the infiltration of a protein known as von Willebrand factor. Tissues from pig valves are commonly used to make human heart-valve replacements.

Getting to grips with seizure prediction

Posted: 07 Nov 2013 07:37 AM PST

A device that could predict when a person with epilepsy might next have a seizure is one step closer to reality thanks to the development of software by researchers in the USA.

Calcium, vitamin D improve bone density in patients taking antiepileptic drugs

Posted: 07 Nov 2013 07:35 AM PST

A recent prospective, randomized, placebo-controlled clinical trial reports that calcium and vitamin D supplementation improves bone density in a group of male veterans with epilepsy who were treated chronically with antiepileptic drugs. These results suggest that risedronate, a bisphosphonate, may help to prevent new vertebral fractures when taken with calcium and vitamin D supplementation.

Hearing through sight: Brain plasticity and why cochlear implants work better for some people than others

Posted: 07 Nov 2013 07:35 AM PST

Cochlear implants allow adults who have become profoundly deaf to recover the ability to understand speech. However, recovery differs between individuals. Activating the visual regions of the brain has proved essential to the satisfactory recovery of hearing, according to a new study.

Special camera detects tumors

Posted: 07 Nov 2013 07:35 AM PST

Cancer patients have the highest probability of recovering if tumors are completely removed. However, tiny clusters of cancer cells are often difficult for surgeons to recognize and remove. A camera makes hidden tumors visible during an operation.

Ants, like humans, can change their priorities

Posted: 07 Nov 2013 07:34 AM PST

For the first time, researchers have discovered that at least in ants, animals can change their decision-making strategies based on experience. They can also use that experience to weigh different options.

Bio patch that can regrow bone

Posted: 07 Nov 2013 07:34 AM PST

Researchers have created an implantable bio patch that regrows bone in a living body, using existing cells. The team created a scaffold seeded with plasmids containing the genetic information for producing bone. The plasmids are absorbed by bone cells already in the body, spurring new growth. Potential applications extend to dentistry.

Nanoparticles can overcome drug resistance in breast cancer cells

Posted: 07 Nov 2013 06:40 AM PST

Nanoparticles filled with chemotherapeutic drugs can kill drug-resistant breast cancer cells, according to a study published.

Defining allergy fact from fiction

Posted: 07 Nov 2013 06:38 AM PST

From gluten allergy and hypoallergenic pets, to avoiding the flu shot because of an egg allergy, there are a lot of common myths and misconceptions about allergies. Many might be shocking due to a great deal of false information in the media and on the Internet. And some of the misconceptions can be damaging to your health.

Common genetic pathway could be conduit to pediatric tumor treatment

Posted: 07 Nov 2013 06:38 AM PST

Investigators have found a known genetic pathway to be active in many difficult-to-treat pediatric brain tumors called low-grade gliomas, potentially offering a new target for the treatment of these cancers.

'Diabetic flies' can speed up disease-fighting research

Posted: 06 Nov 2013 05:22 PM PST

In a finding that has the potential to significantly speed up diabetes research, scientists have discovered that fruit flies respond to insulin at the cellular level much like humans do, making these common, easily bred insects good subjects for laboratory experiments in new treatments for diabetes.

Collaborative efforts help mental health patients quit smoking

Posted: 06 Nov 2013 05:18 PM PST

To combat reliance on tobacco in mental health populations, experts agree that mental health services and government-sponsored tobacco control programs must work together to improve education and access to smoking cessation programs.

Hormone levels in women using contraception affect nerve activity involved in vessel constriction

Posted: 06 Nov 2013 12:22 PM PST

Latest research provides new insight into mechanisms through which lower hormone levels may make the body more susceptible to damage caused by stress and the chronic elevation of the fight or flight response. A pattern consistent with these findings is observed in postmenopausal women.

Brain may play key role in blood sugar metabolism, development of diabetes

Posted: 06 Nov 2013 11:13 AM PST

New research suggests that the development of diabetes Type 2 requires a failure of both the islet-cell system in the pancreas and a brain-centered system for regulating blood sugar levels. Boosting insulin levels alone will lower glucose levels, but only addresses half the problem. Restoring normal glucose regulation requires addressing failures of the brain-centered system as well. Approaches that target both systems could actually cause diabetes to go into remission.

Researchers help make pediatric eye cancer easier to detect

Posted: 06 Nov 2013 11:13 AM PST

Can parents use digital cameras and smart phones to potentially screen their children for the most common form of pediatric eye cancer? Researchers believe so.

Hospitals with neurology residency programs more likely to administer life-saving stroke drugs

Posted: 06 Nov 2013 10:18 AM PST

Stroke patients treated at hospitals with neurology residency programs are significantly more likely to get life-saving clot-busting drugs than those seen at other teaching or non-teaching hospitals, new research suggests.

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