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Saturday, February 2, 2013

ScienceDaily: Top Health News

ScienceDaily: Top Health News


Humanitarian aid workers in Uganda show signs of stress, depression, and burnout

Posted: 01 Feb 2013 04:24 PM PST

The high risk for mental health problems among staff working in humanitarian organizations in northern Uganda is due in large part to their work environment. Scientists examined the mental health of 376 Ugandan workers at 21 humanitarian aid agencies and found that a significant number of the staff at these organizations experienced high levels of symptoms for depression (68 percent), anxiety disorders (53 percent), and posttraumatic stress disorder (26 percent), respectively.

Automated breast density test identifies women at high cancer risk

Posted: 01 Feb 2013 04:22 PM PST

Researchers have developed a novel computer algorithm to easily quantify a major risk factor for breast cancer based on analysis of a screening mammogram. Increased levels of mammographic breast density have been shown in multiple studies to be correlated with elevated risk of breast cancer, but the approach to quantifying it has been limited to the laboratory setting where measurement requires highly skilled technicians. This new discovery opens the door for translation to the clinic where it can be used to identify high-risk women for tailored treatment.

New study sheds light on link between dairy intake and bone health: Not all dairy products are equal

Posted: 01 Feb 2013 10:23 AM PST

A new study has found that dairy intake -- specifically milk and yogurt -- is associated with higher bone mineral density in the hip, but not the spine.

Needless abdominal CT scans can be avoided in children, study says

Posted: 01 Feb 2013 10:23 AM PST

A study of more than 12,000 children from emergency departments throughout the U.S. has identified seven factors that can help physicians determine the need for a computed tomography scan following blunt trauma to the abdomen.

Novel radiation therapy method shortens prostate cancer treatment time

Posted: 01 Feb 2013 08:44 AM PST

The use of volume-modulated arc therapy to deliver intensity-modulated radiation therapy to prostate cancer patients results in an overall reduction in treatment time of approximately 14 percent, a new study suggests.

Physical activity and modernization: Heart disease indicators almost non-existent among Tsimane, indigenous population

Posted: 01 Feb 2013 07:02 AM PST

Heart disease continues to be the leading cause of death in the United States, and a sedentary lifestyle is often cited as a major contributing factor. Among the Tsimane, an indigenous population in the lowlands of Bolivia's Amazon basin, however, indicators of heart disease are practically non-existent –– cholesterol is low, obesity is rare, and smoking is uncommon.

Genetically modified tobacco plants produce antibodies to treat rabies

Posted: 01 Feb 2013 07:02 AM PST

Smoking tobacco is bad for your health, but a genetically altered version of the plant might provide an inexpensive cure for the deadly rabies virus. Scientists have produced a monoclonal antibody in transgenic tobacco plants shown to neutralize the rabies virus. This antibody works by preventing the virus from attaching to nerve endings around the bite site and keeping the virus from traveling to the brain.

If you are impulsive, take modafinil and count to ten, research suggests

Posted: 01 Feb 2013 07:01 AM PST

Poor impulse control contributes to one's inability to control the consumption of rewarding substances, like food, alcohol, and other drugs. This can lead to the development of addiction. FDA-approved medications for alcoholism, like naltrexone (Revia) and disulfiram (Antabuse), are thought to reduce alcohol consumption by curbing cravings and creating unpleasant reactions to alcohol, effects which reduce the desire to drink alcohol.

Excess sugar linked to cancer

Posted: 01 Feb 2013 07:01 AM PST

Sugars are needed to provide us with energy and in moderate amounts contribute to our well-being. Sustained high levels of sugars, as is found in diabetics, damages our cells and now is shown that can also increase our chance to get cancer: The dose makes the poison as Paracelsus said.

Treatment to prevent Alzheimer's disease moves a step closer

Posted: 01 Feb 2013 07:01 AM PST

A new drug to prevent the early stages of Alzheimer's disease could enter clinical trials in a few years' time, according to scientists.

Quantum dots deliver vitamin D to tumors for possible inflammatory breast cancer treatment

Posted: 01 Feb 2013 06:59 AM PST

Quantum dots can be used to rapidly move high concentrations of the active form of Vitamin D to targeted tumor sites where cancer cells accumulate.

Propping open the door to the blood brain barrier

Posted: 01 Feb 2013 06:59 AM PST

A new approach to delivering therapeutics could lead to better treatment of central nervous system disorders.

Tracking the evolution of antibiotic resistance

Posted: 01 Feb 2013 06:59 AM PST

An automated device is yielding a new understanding of how antibiotic resistance evolves at the genetic level.

Type II diabetes and Alzheimer's connection

Posted: 01 Feb 2013 06:59 AM PST

A research team has devised a novel approach to identifying the molecular basis for designing a drug that might one day decrease the risk diabetes patients face of developing Alzheimer's disease.

Nanomechanical signature of breast cancer

Posted: 01 Feb 2013 06:59 AM PST

Differences in the stiffness of cancerous versus healthy tissue may aid in diagnosis and therapy, researchers say.

Listening to Cells: Scientists probe human cells with high-frequency sound

Posted: 01 Feb 2013 06:59 AM PST

Researchers have developed a new non-contact, non-invasive tool to measure the mechanical properties of cells at the sub-cell scale.

Imaging unveils temperature distribution inside living cells

Posted: 01 Feb 2013 06:59 AM PST

A new breakthrough marks the first time anyone has been able to show the actual temperature distribution inside living cells.

Group therapy: New approach to psychosis treatment

Posted: 01 Feb 2013 06:59 AM PST

A new understanding of how the brain's G-protein receptors work may soon enable a way to better customize and target antipsychotic drugs to treat specific symptoms.

Autism speaks through gene expression

Posted: 01 Feb 2013 06:59 AM PST

Autism spectrum disorders affect nearly 1 in 88 children, with symptoms ranging from mild personality traits to severe intellectual disability and seizures. New work examines which genes are responsible for autism disorders.

New stroke gene discovery could lead to tailored treatments

Posted: 01 Feb 2013 06:08 AM PST

Scientists have identified a new genetic variant associated with stroke. By exploring the genetic variants linked with blood clotting -- a process that can lead to a stroke -- scientists have discovered a gene which is associated with large vessel and cardioembolic stroke but has no connection to small vessel stroke.

Target 'super-spreaders' to stop hepatitis C

Posted: 01 Feb 2013 06:08 AM PST

Each intravenous drug user contracting hepatitis C is likely to infect around 20 other people with the virus, half of these transmissions occurring in the first two years after the user is first infected, a new study estimates.

Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases

Posted: 01 Feb 2013 06:08 AM PST

A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study.

Fight against river blindness is successful and inexpensive

Posted: 01 Feb 2013 06:08 AM PST

A relatively inexpensive program set up to combat river blindness has resulted in major health improvements in Africa, shows a new study. The study shows that US $250 million helped cure or prevent the major symptoms of onchocerciasis in millions of people.

Bioelectric signals can be used to detect early cancer

Posted: 01 Feb 2013 06:08 AM PST

Biologists have discovered a bioelectric signal that can identify cells that are likely to develop into tumors. The researchers also found that they could lower the incidence of cancerous cells by manipulating the electrical charge across cells' membranes.

Getting fit fast: Inactive people can achieve major health and fitness gains in a fraction of the time

Posted: 01 Feb 2013 06:04 AM PST

With many of us struggling to get enough exercise, sport and exercise scientists have been working on a time-saving solution.

Cats and humans suffer from similar forms of epilepsy

Posted: 01 Feb 2013 06:03 AM PST

Epilepsy affects the very core of our being, our brain.  Epileptic attacks can lead to seizures throughout the body or in parts of it. Clouding of consciousness or memory lapses are also possible.  The causes are still only partially understood but in some cases brain tumors, infections, inflammations of the brain or metabolic diseases have been implicated.

Blood vessel cells coax colorectal cancer cells into more dangerous state

Posted: 01 Feb 2013 05:22 AM PST

Blood vessels that supply oxygen and nutrients to tumors can also deliver something else - a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and more lethal, scientists report.

Transition in cell type parallels treatment response, disease progression in breast cancer

Posted: 31 Jan 2013 11:43 AM PST

A process that normally occurs in developing embryos -- the changing of one basic cell type into another -- has also been suspected of playing a role in cancer metastasis. Now a study has associated this process, called epithelial-mesenchymal transition or EMT, with disease progression and treatment response in breast cancer patients. The report also identifies underlying mechanisms that someday may become therapeutic targets.

Understanding 'master regulator' genes could lead to better cancer treatments

Posted: 31 Jan 2013 11:43 AM PST

A pair of genes work together as "master regulators" in cell division to keep the correct number of chromosomes in each daughter cell. Ipl1 and Mps1 work to hook and unhook chromosomes for proper DNA separation. The discovery could lead to better anti-cancer therapies.

More links found between schizophrenia and cardiovascular disease

Posted: 31 Jan 2013 11:41 AM PST

A new study expands and deepens the biological and genetic links between cardiovascular disease and schizophrenia. Cardiovascular disease is the leading cause of premature death among schizophrenia patients, who die from heart and blood vessel disorders at a rate double that of persons without the mental disorder.

New target for treating wide range of cancers: Promising binding site on mutant p53 protein

Posted: 31 Jan 2013 09:13 AM PST

Biologists, chemists and computer scientists have identified an elusive pocket on the surface of the p53 protein that can be targeted by cancer-fighting drugs. The finding heralds a new treatment approach, as mutant forms of this protein are implicated in nearly 40 percent of diagnosed cases of cancer, which kills more than half a million Americans each year.

A new mechanism that contributes to the evolution of cancer

Posted: 31 Jan 2013 09:13 AM PST

A new study demonstrates the existence of new fragile genomic sites responsible for chromosomal alterations in tumors. This novel mechanism explains up to 50 percent of the abnormalities associated with some types of leukemia.

How the tilt of a cell-surface receptor prevents cancer

Posted: 31 Jan 2013 09:10 AM PST

Clear communication between cells is essential to every aspect of the body's internal function. But since cells can't talk, or send emails, how do they communicate? The answer, in a nutshell, is by dispatching signaling molecules that selectively bind to protein receptors on the outer surface of other cells with which they must "talk."

Second-generation CT scanner substantially reduces radiation exposure

Posted: 31 Jan 2013 09:10 AM PST

Researchers using a newly approved advanced computed tomography (CT) system were able to significantly reduce radiation exposure in patients undergoing coronary CT angiography, according to a new study.

Rehabilitation therapies can lead to recovery from chronic fatigue syndrome

Posted: 31 Jan 2013 09:08 AM PST

Recovery from chronic fatigue syndrome is possible for some patients, and new research has identified two treatments most likely to lead to recovery.

Personalized medicine eliminates need for drug in two children

Posted: 31 Jan 2013 09:07 AM PST

The risk of hypertension was eliminated with $10K savings per patient through genomics.

First human induced pluripotent stem cells from patients with maturity onset diabetes of the young

Posted: 31 Jan 2013 09:06 AM PST

Scientists report the first generation of human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes of the young (MODY). These cells offer a powerful resource for studying the role of genetic factors in the development of MODY and testing potential treatments.

Novel pathway for a mucosal TB vaccine

Posted: 31 Jan 2013 09:06 AM PST

A new pathway for improving vaccines against tuberculosis has been discovered by microbiologists.

Hit by two hammers: How deficiencies in two genes synergize to halt formation of gut nervous system

Posted: 31 Jan 2013 06:50 AM PST

A genetic analysis has implications for a genetic disorder known as Hirschsprung Syndrome.

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