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Friday, October 19, 2012

ScienceDaily: Top Health News

ScienceDaily: Top Health News


Tissue-engineered kidneys: Researchers make important strides

Posted: 18 Oct 2012 03:48 PM PDT

With a worldwide shortage of kidneys for patients who need kidney transplants, researchers are diligently working to find ways to engineer new kidney tissue from a patient's own cells or another source. They've come a step closer to realizing that goal with a breakthrough described in a new study. The advance could lead to more options for individuals with kidney failure, as well as better tools for understanding kidney diseases and how to treat them.

New way to save blood from ravages of chemo treatment

Posted: 18 Oct 2012 01:26 PM PDT

Chemotherapy kills blood cells as well as cancer cells, often with fatal results. Now stem cell researchers have identified a method they hope one day will help cancer patients undergoing chemotherapy maintain a healthy blood supply, they report.

First-of-its-kind self-assembled nanoparticle for targeted and triggered thermo-chemotherapy

Posted: 18 Oct 2012 01:22 PM PDT

Researchers describe the design and effectiveness of a first-of-its-kind, self assembled, multi-functional, NIR responsive gold nanorods that delivers a chemotherapy drug specifically targeted to cancer cells and selectively release the drug in response to an external beam of light while creating heat for synergistic thermo-chemo mediated anti-tumor efficacy.

Study succeeds in cutting inappropriate antibiotic prescribing by pediatricians

Posted: 18 Oct 2012 01:22 PM PDT

A study involving one of the nation's largest networks of pediatric practices was able to nearly halve the inappropriate use of antibiotics through quarterly monitoring and feedback of the physicians' prescribing patterns. The research is one of the first to look at an antimicrobial stewardship intervention in the outpatient setting.

Hospital uses ‘lean’ manufacturing techniques to speed stroke care

Posted: 18 Oct 2012 01:20 PM PDT

A hospital stroke team used auto industry "lean" manufacturing principles to accelerate treatment times, according to new research.

Mechanisms of action for green tea extract in breast cancer prevention identified

Posted: 18 Oct 2012 12:19 PM PDT

An oral green tea extract, Polyphenon E, appears to inhibit vascular endothelial growth factor and hepatocyte growth factor, both of which promote tumor cell growth, migration and invasion.

Blood hormone levels predicted long-term breast cancer risk for postmenopausal women

Posted: 18 Oct 2012 12:19 PM PDT

Blood hormone tests predicted a woman's risk for developing postmenopausal breast cancer for up to 20 years, according to new research.

High levels of estradiol, progesterone during pregnancy associated with increased risk for HR-negative breast cancer

Posted: 18 Oct 2012 12:19 PM PDT

Increased concentrations of the pregnancy hormones estradiol and progesterone were associated with an increased risk for hormone receptor-negative breast cancer diagnosed before age 50, according to the results of a nested case-control study.

Depression, shortened telomeres increase mortality in bladder cancer patients

Posted: 18 Oct 2012 11:18 AM PDT

Low depressive symptoms and a longer telomere length are compelling factors that contribute to a prolonged life for bladder cancer patients, according to researchers.

Elevated risk of blood clots in women taking birth control containing drospirenone, study shows

Posted: 18 Oct 2012 11:18 AM PDT

New research has found an increased risk of arterial thrombotic events and venous thromboembolic events -- commonly referred to as blockage of arteries and blood clots, respectively -- associated with drospirenone-containing birth control pills compared to four low-dose estrogen combined hormonal contraceptives.

No antibodies, no problem: Researchers identify how mosquito immune system attacks specific infections

Posted: 18 Oct 2012 10:40 AM PDT

Researchers have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene. Unlike humans and other animals, insects do not make antibodies to target specific infections.

Norovirus outbreaks in nursing homes associated with increase in hospitalizations, risk of death

Posted: 18 Oct 2012 10:09 AM PDT

In a study that included more than 300 Medicare-certified nursing homes, rates of hospitalization and death were substantially increased during outbreaks of norovirus gastroenteritis vs. non-outbreak periods.

Ultraviolet light effective in hospital infection control, study suggests

Posted: 18 Oct 2012 10:09 AM PDT

A specific spectrum of ultraviolet light killed certain drug-resistant bacteria on the door handles, bedside tables and other surfaces of hospital rooms, suggesting a possible future weapon in the battle to reduce hospital-associated infections.

Reprogrammed amniotic fluid cells could treat vascular diseases

Posted: 18 Oct 2012 09:33 AM PDT

Scientists have discovered a way to utilize diagnostic prenatal amniocentesis cells, reprogramming them into abundant and stable endothelial cells capable of regenerating damaged blood vessels and repairing injured organs.

Developed a technology that predicts metastasis in breast cancer

Posted: 18 Oct 2012 09:33 AM PDT

Researchers have developed a diagnostic tool that identifies the metastatic ability of breast cancer cells. The analysis is based on the characterization of the lipid component of the cells, which is indicative of malignancy.

Mutation that causes skin hyperproliferation identified

Posted: 18 Oct 2012 09:33 AM PDT

Scientists have identified a mutation in a gene that causes patches of very thick skin to appear on the palms and soles of affected people. This skin disorder is related, albeit in a much milder form, to that of the Indonesian "Tree Man", Dede Koswara.

Genes and immune system shaped by childhood poverty, stress

Posted: 18 Oct 2012 09:30 AM PDT

New research has revealed that childhood poverty, stress as an adult, and demographics such as age, sex and ethnicity, all leave an imprint on a person's genes. And, that this imprint could play a role in our immune response.

Scientists harness immune system to prevent lymphoma relapse

Posted: 18 Oct 2012 09:30 AM PDT

Scientists hope that lymphoma patients could benefit from a new drug that triggers the cancer-fighting properties of the body's own immune system, after highly promising early laboratory results.

Rethinking toxic proteins on the cellular level: Lipid droplets play an unexpected role in embryo development

Posted: 18 Oct 2012 09:30 AM PDT

Histones are proteins needed to assemble DNA molecules into chromosomes. They have long represented a classic balancing act in biology; too few histone molecules result in DNA damage, while too many histones are toxic to the cell. New research is causing a fundamental shift in the concept of histone balance and the mechanism behind it.

Treating vascular disorders with a cell-based strategy

Posted: 18 Oct 2012 09:30 AM PDT

A new approach for generating large numbers of circulatory system cells, known as vascular endothelial cells (VECs), from human amniotic-fluid-derived cells is reported in a new study. The strategy, which shows promise in mice, opens the door to establishing a vast inventory of VECs for promoting organ regeneration and treating diverse vascular disorders.

From the twitching whiskers of babes: Naptime behavior shapes the brain

Posted: 18 Oct 2012 09:30 AM PDT

The whiskers of newborn rats twitch as they sleep, in a whisker equivalent of rapid-eye-movements, and that could open the door to new understandings about the intimate connections between brain and body. The discovery reinforces the notion that such involuntary movements are a vital contributor to the development of sensorimotor systems, say researchers.

Value of combined approach to quitting smoking confirmed

Posted: 18 Oct 2012 09:20 AM PDT

Smokers who try to quit would be more successful if they combined medication or nicotine-replacement therapy with behavioral counseling, finds a new review.

Breast-feeding reduced risk for ER/PR-negative breast cancer, results find

Posted: 18 Oct 2012 09:19 AM PDT

Breast-feeding reduced the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to new results.

Green tea reduced inflammation, may inhibit prostate cancer tumor growth, research finds

Posted: 18 Oct 2012 09:19 AM PDT

Men with prostate cancer who consumed green tea prior to undergoing prostatectomy had reductions in markers of inflammation, according to new data

Compound's dual action inhibited oral cancer, rat study finds

Posted: 18 Oct 2012 09:19 AM PDT

The compound licofelone inhibited oral cancer growth by inhibiting the cyclooxygenase and 5-lipoxygenase pathways, with no observable side effects, according to a recent rat study.

Viruses act like 'self-packing suitcases'

Posted: 18 Oct 2012 07:32 AM PDT

Researchers have identified a crucial stage in the lifecycle of simple viruses like polio and the common cold that could open a new front in the war on viral disease.

Short booms still annoying: How mid-level noise bursts affect concentration of arithmetic-solving test subjects

Posted: 18 Oct 2012 07:29 AM PDT

Noise can be distracting, especially to a person trying to concentrate on a difficult task. Studying annoying noises helps architects design better building environments and policy makers choose effective noise regulations. To better understand how short noise bursts affect humans' mental state, researchers played quarter-second-long white noise clips to test subjects as they worked on arithmetic problems. The researchers noticed a slight general trend toward lower performance when louder noises were played, and also identified sound level ranges that caused participants to report significant levels of annoyance.

Helmet-to-helmet collisions: Scientists model how vibrations from football hits wobble the brain

Posted: 18 Oct 2012 07:29 AM PDT

Hard collisions can lead to player concussions, but the physics of how the impact of a helmet hit transfers to the brain are not well understood. A research team has created a simplified experimental model of the brain and skull inside a helmet during a helmet-to-helmet collision.

Decreased gene activity is likely involved in childhood risk for anxiety and depression

Posted: 18 Oct 2012 07:27 AM PDT

Decreased activity of a group of genes may explain why in young children the "fear center" of the anxious brain can't learn to distinguish real threats from the imaginary, according to a new study.

New drug to target and destroy tumor cells developed: Minnelide gives new hope for treating pancreatic cancer

Posted: 18 Oct 2012 07:27 AM PDT

Researchers have developed new drug to target tumor cells in pancreatic cancer. The study is based on successful outcomes in a mouse model -- results researchers expect to carry over to human patients when the drug potentially begins human trials in 2013. The drug, Minnelide, is a type of injectable chemotherapy designed to target tumor cells. The drug works by inhibiting a heat shock protein, HSP 70, which has been proven to aid the growth of tumor cells. By stopping HSP 70 from working, Minnelide disperses the cells integral to the tumor's growth and the cancer disintegrates.

Weight loss does not improve fertility, but does improve sexual function, research finds

Posted: 18 Oct 2012 07:27 AM PDT

Losing weight does not necessarily lead to improved fertility in women, but it can improve sexual function, according to a recent study that followed morbidly obese women of reproductive age for up to two years after Roux en Y gastric bariatric bypass surgery

Antibiotic shows promise in treating extensively drug-resistant tuberculosis

Posted: 18 Oct 2012 07:27 AM PDT

When tested in patients hospitalized with extensively drug-resistant tuberculosis (XDR-TB) unresponsive to previous treatment, linezolid, an antibiotic used to treat severe bacterial infections, proved largely effective when added to the patients' ongoing TB treatment regimen.

American Academy of Pediatrics renews commitment to preventing gun injuries in children

Posted: 18 Oct 2012 07:27 AM PDT

The American Academy of Pediatrics is renewing its call to reduce the destructive effects of guns in the lives of children and adolescents, including counseling parents about safe gun storage as well as supporting legislation to prevent firearm injuries and deaths.

Women whose first pregnancy was ectopic have fewer children and high risk of another ectopic pregnancy

Posted: 18 Oct 2012 07:01 AM PDT

Women whose first pregnancy is ectopic are likely to have fewer children in the following 20-30 years than women whose first pregnancy ends in a delivery, miscarriage or abortion, according to results from a study of nearly 3,000 women in Denmark. In addition, these women have a five-fold increased risk of a subsequent ectopic pregnancy.

Fear really resides in a different area of the brain than its inhibitory mechanisms

Posted: 18 Oct 2012 07:01 AM PDT

Do you suffer from a phobia? Maybe arachnophobia? Then you know very well that even if you do not feel uneasy when imagining a huge and hairy tarantula in the therapist's office, you still jump out of the shower screaming upon seeing a tiny spider. Why is it so hard to get rid of a phobia?

Non-infected babies born to HIV mothers have reduced immunity to measles

Posted: 18 Oct 2012 07:01 AM PDT

Non-infected babies born to HIV positive mothers should be vaccinated early against measles, to avoid them acquiring the virus or passing it on to others, according to researchers. A new study finds that even if babies are born without HIV, their maternally derived protection against measles may be impaired by their mother's positive HIV status.

Device to help stutterers: Interdisciplinary team developing prosthetic as part of a complete treatment program

Posted: 18 Oct 2012 06:48 AM PDT

Researchers have created a patent-pending device that could change the lives of people who stutter.

New target for treating diabetic kidney disease, the leading cause of kidney failure

Posted: 18 Oct 2012 06:48 AM PDT

Researchers have discovered a new therapeutic target for diabetic nephropathy, the leading cause of kidney failure. The findings could help protect the kidney health of individuals with diabetes.

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